Recombinant Cynomolgus IGF1R/CD221 Protein

N-糖苷酶F(PNGaseF)是一种酰胺水解酶，经过和平空间站伊丽莎菌克隆，主要由脑膜炎脓杆菌等革兰氏阴性菌分泌。酵母重组表达N-糖苷酶F（比活性：750000U/mL），可以裂解由天冬酰胺连接的高甘露糖、杂合和复杂的寡糖糖蛋白。PNGaseF的切割位点为糖蛋白内侧N-乙酰葡萄糖胺（GlcNAc）和天冬酰氨残基之间的酰胺键，同时将酶解后蛋白上的天冬氨酰转化为天冬氨酸。本产品带his标签，常应用于抗体及其相关蛋白完全去糖基化。另外，我司还提供其他类型的糖苷酶，包括酵母重组表达的N-糖苷酶F，糖苷内切酶H，糖苷内切酶S。产品信息产品性质中文别名（Chinesesynonym）N-糖酰胺酶F；N-糖苷酶F英文别名（Englishsynonym）PNGaseF来源（Source）酵母重组表达分子量（Molecularweight）36kDa比活性（Specificactivity）750000U/mL缓冲液组分（Buffer）20mMTris-HClpH7.5,50mMNaCl,5mMEDTA,50%GlycerolRANTES是对单核细胞，记忆T细胞（CD4+/CD45RO），嗜碱性粒细胞和嗜酸性粒细胞的趋化剂。Recombinant Cynomolgus IGF1R/CD221 Protein,His Tag

PE-labeled Human HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Tetramer Protein,His-Avi Tag性能参数表达区间及表达系统（Source）PE-labeledHumanHLA-A*02:01&B2M&P53R175H(HMTEVVRHC)TetramerProteinisexpressedfromHEK293withHistagandAvitagattheC-Terminus.PE-labeledHumanHLA-A*02:01&B2M&P53R175H(HMTEVVRHC)TetramerisassembledbybiotinylatedmonomerandPE-labeledstreptavidin.ItcontainsGly25-Thr305(HLA-A*02:01),Ile21-Met119(B2M)andHMTEVVRHCpeptide.（Endotoxin）Lessthan1EUperμgbytheLALmethod.制剂（Formulation）Suppliedas0.22μmfilteredsolutionin20mMPB,500mMNaCl,0.2%BSA(pH8.0).储存条件Theproductshouldbestoredat-85~-65℃for3monthfromdateofreceipt.Recommendtoaliquottheproteinintosmallerquantitieswhenfirstusedandavoidrepeatedfreeze-thawcycles.Recombinant Cynomolgus GDF15 Protein,hFc Tag鼠AFGF与人AFGF具有96％的氨基酸序列身份，因此它在鼠和人AFGF之间表现出相当大的物种交叉反应性。

Angiotensin I Converting Enzyme (ACE-2), also called ACEH (ACE homologue), is a dimeric, zinc-dependent metalloprotease of the ACE family that also includes somatic and germinal ACE. ACE-2 mRNA is found at high levels in heart, testis, and kidney and at lower levels in a wide variety of tissues. ACE-2 is the SARS-CoV and SARS-CoV2 Spike protein receptor in vivo, functions catalytically as a carboxypeptidase to cleave several substrates including angiotensins I and II, and acts as a partner for B0AT1-family amino acid transporters. Through these functions, ACE-2 has been shown to be involved in several diseases including SARS, COVID19, acute lung injury, heart disease, liver and lung fibrosis, inflammatory lung disease, and cardiopulmonary disease . Full length ACE-2 protein includes an extracellular region composed of a single N-terminal peptidase domain and C-terminal collectrin-like domain (CLD), a transmembrane domain, and a short cytoplasmic tail. The N-terminal peptidase region is required for binding to SARS-CoV and SARS-CoV2 spike proteins, while the CLD contains a region that promotes dimerization and association with amino acid transporters.

透明质酸酶，英文名称Hyaluronidase，一类能够降低体内透明质酸活性的酶的总称，结构上由4个相同亚基构成，每个亚基分子量接近14kDa，该酶是一种糖蛋白，包含5%的甘露糖和2.2%的葡萄糖胺。功能上该酶可随机裂解透明质酸、软骨素和硫酸软骨素中的β-N-乙酰己糖胺-[1→4]糖苷键。常与胶原酶联合使用于降解细胞外基质，从而从组织中分离活细胞。本品来源于牛睾丸，活力值为400–1,000units/mg，合适的pH值为4.5–6.0。产品性质中文别名（ChineseSynonym）玻璃糖醛酸酶；玻璃酸酶英文别名（EnglishSynonym）Hyaluronoglucosaminidase；Hyaluronate4-glycanohydrolaseCAS号（CASNO.）37326-33-3来源（Source）牛睾丸分子量（MolecularWeight）~55kDa类型（Type）I-S外观（Appearance）淡黄色至米黄色至褐色粉末OSM与白血病抑制因子（LIF）密切相关，实际上，除了其在人类中的特定受体外，它实际上还使用了LIF受体。

Name:4-1BBR/TNFRSF9,Human同义:Tnfrsf9,CD137抗原,T细胞抗原ILA描述:4-1bb受体,也称tnfrsf9是tnf超家族受体的一个成员。它主要表达在各种T细胞表面,但也存在于B细胞、单核细胞和各种转化细胞系中。4-1bb受体结合到4-1bbl,为T淋巴细胞提供共同刺激信号。4-1b受体的信号传递与抗原表达过程和细胞毒性T细胞的生成有关。物种:人类资料来源:E。大肠杆菌生物活性:与标准相比具有完全生物活性。利用人外周血单核细胞产生的IL8的抑制作用决定了其生物活性。在4-1bb配体和4-1bb受体中,大约90%的IING都是用1g浓度进行的。格斯序列缩短:分子式:C终端:分子量:测量的分子量:大约17.7kda,一个含有166个氨基酸的非糖化多肽链。Purity:>97%bySDS-PAGEandHPLCanalyses.配方:用10mmPb,PH8.0,150mm纳克尔过滤浓缩液冻干.重建:我们建议在开瓶前先将此瓶简单离心,以便将其放在底部。在无菌蒸馏水或含有0.1%BSA的水缓冲液中再形成浓度为0.1-1.0毫克/毫升。库存解决方案应分配到工作参数中,并在20℃处储存。应在适当的缓冲解决方案中进一步稀释。水平:Lal法测定的Rhu4-1b受体小于1欧盟/克。储藏:无菌过滤白干冻干粉。通过泛素-蛋白体途径(UPP)中的酶与底物蛋白共价连接，并在26S蛋白体降解ATP依赖的细胞蛋白中发挥主要作用。Recombinant Human TREM2 Protein,hFc Tag

糖苷酶 F (PNGase F)是一种酰胺水解酶，经过和平空间站伊丽莎菌克隆，主要由脑膜炎脓杆菌等革兰氏阴性菌分泌。Recombinant Cynomolgus IGF1R/CD221 Protein,His Tag

SARS-CoV-2, which causes the global pandemic coronavirus disease 2019 (Covid-19), belongs to a family of viruses known as coronaviruses that also include MERS‑CoV and SARS-CoV-1. Coronaviruses are commonly comprised of four structural proteins: Spike protein (S), Envelope protein (E), Membrane protein (M) and Nucleocapsid protein (N). The SARS-CoV-2 S protein is a glycoprotein that mediates membrane fusion and viral entry. The S protein is homotrimeric, with each ~180-kDa monomer consisting of two subunits, S1 and S2 .The RBD of SARS-CoV-2 binds a metallopeptidase, angiotensin-converting enzyme 2 (ACE-2). Before binding to the ACE-2 receptor, structural analysis of the S1 trimer shows that only one of the three RBD domains is in the "up" conformation. This is an unstable and transient state that passes between trimeric subunits but is nevertheless an exposed state to be targeted for neutralizing antibody therapy. Polyclonal antibodies to the RBD of the SARS-CoV-2 protein have been shown to inhibit interaction with the ACE-2 receptor, confirming RBD as an attractive target for vaccinations or antiviral therapy.  Recombinant Cynomolgus IGF1R/CD221 Protein,His Tag

浦斯瑞（上海）生物医药有限公司汇集了大量的优秀人才，集企业奇思，创经济奇迹，一群有梦想有朝气的团队不断在前进的道路上开创新天地，绘画新蓝图，在江苏省等地区的化工中始终保持良好的信誉，信奉着“争取每一个客户不容易，失去每一个用户很简单”的理念，市场是企业的方向，质量是企业的生命，在公司有效方针的领导下，全体上下，团结一致，共同进退，**协力把各方面工作做得更好，努力开创工作的新局面，公司的新高度，未来浦斯瑞（上海）生物医药供应和您一起奔向更美好的未来，即使现在有一点小小的成绩，也不足以骄傲，过去的种种都已成为昨日我们只有总结经验，才能继续上路，让我们一起点燃新的希望，放飞新的梦想！